Upper GI disease cases are climbing worldwide, but care quality is finally catching up — unevenly.
Qunying Zhao
Drawing on the Global Burden of Disease 2021 dataset, this analysis shows that cases of GERD, peptic ulcer disease, and gastritis/duodenitis rose sharply worldwide between 1990 and 2021, even as age-adjusted mortality fell and a global quality-of-care index climbed. Lower-income regions lagged behind in care quality but improved the fastest, while GERD's burden kept rising even as peptic ulcer and gastritis burdens declined. The authors call for disease-specific strategies and stronger health-system support in low-resource settings to close the remaining gaps.
- The question: How have reflux, ulcers, and gastritis changed worldwide, and is care keeping pace?
- The study: Using the Global Burden of Disease 2021 dataset, this analysis tracked GERD, peptic ulcer disease, and gastritis from 1990 to 2021.
- The finding: Cases rose sharply worldwide, yet GERD's burden kept climbing while peptic ulcer and gastritis burdens declined.
- The nuance: Age-adjusted mortality fell and quality of care improved, and lower-income regions lagged behind but improved the fastest.
Takeaway: use disease-specific strategies and stronger health-system support in low-resource settings.
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